Genetic blood disorder may explain tragedy of Henry VIII

According to a new study, multiple miscarriages and dramatic personality transformation may be linked to a genetic condition related to the blood group carried by King Henry VIII of England.

The study by bioarchaeologist Catrina Banks, published in The Historical Journal (Cambridge University Press), states that Henry may have belonged to the Kell blood group, a condition that could both trigger miscarriages in partners, and McLeod syndrome, a genetic disorder specific to the Kell blood group, which "would finally provide an explanation for his shift in both physical form and personality from a strong, athletic, generous individual in his first 40 years to the monstrous paranoiac he would become, virtually immobilized by massive weight gain and leg ailments."